Secondary prophylaxis for rheumatic fever: simple concepts, difficult delivery.

[acute rheumatic fever]

Registers of those with rheumatic heart disease or a history of acute rheumatic fever (RF ) are key to prevent RF recurrences and improve disease control . Randomized controlled trials show intramuscular long -acting benzathine penicillin G is more effective than oral penicillin to prevent recurrences . Although some guidelines recommend three -weekly benzathine penicillin , four weekly is effective if compliance rates are high . Four -weekly penicillin delivery is also preferable to three -weekly regimens for health resource and logistical reasons and for patient acceptability and compliance .

Diseases
Validation

Diseases presenting "heart disease" symptom

22q11.2 deletion syndrome

achondroplasia

acute rheumatic fever

adrenal incidentaloma

child syndrome

classical phenylketonuria

cohen syndrome

congenital diaphragmatic hernia

dentinogenesis imperfecta

esophageal adenocarcinoma

fabry disease

familial mediterranean fever

heparin-induced thrombocytopenia

hirschsprung disease

holt-oram syndrome

homocystinuria without methylmalonic aciduria

kabuki syndrome

monosomy 21

omenn syndrome

phenylketonuria

sneddon syndrome

systemic capillary leak syndrome

wiskott-aldrich syndrome

wolf-hirschhorn syndrome

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