Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Prevalence of Group A beta-haemolytic Streptococcus isolated from children with acute pharyngotonsillitis in Aden, Yemen.
[acute rheumatic fever]
To
estimate
the
prevalence
of
Group
A
beta
-haemolytic
streptococcus
(
GAS
)
and
non-
GAS
infections
among
children
with
acute
pharyngotonsillitis
in
Aden
,
Yemen
,
to
evaluate
the
value
of
a
rapid
diagnostic
test
and
the
McIsaac
score
for
patient
management
in
this
setting
and
to
determine
the
occurrence
of
emm
genotypes
among
a
subset
of
GAS
isolated
from
children
with
acute
pharyngotonsillitis
and
a
history
of
acute
rheumatic
fever
(
ARF
)
or
rheumatic
heart
disease
(
RHD
)
.
Group
A
beta
-haemolytic
streptococcus
infections
in
school
-aged
children
with
acute
pharyngotonsillitis
in
Aden
,
Yemen
,
were
diagnosed
by
a
rapid
GAS
antigen
detection
test
(
RADT
)
and
/
or
GAS
culture
from
a
throat
swab
.
The
RADT
value
and
the
McIsaac
screening
score
for
patient
management
were
evaluated
.
The
emm
genotype
of
a
subset
of
GAS
isolates
was
determined
.
Group
A
beta
-haemolytic
streptococcus
pharyngotonsillitis
was
diagnosed
in
287
/
691
(
41
.
5
%
;
95
%
CI
37
.
8
-
45
.
3
)
children
.
Group
B
,
Group
C
and
Group
G
beta
-haemolytic
streptococci
were
isolated
from
4
.
3
%
children
.
The
RADT
had
a
sensitivity
of
238
/
258
(
92
.
2
%
)
and
specificity
of
404
/
423
(
95
.
5
%
)
against
GAS
culture
.
A
McIsaac
score
of
≥
4
had
a
sensitivity
of
93
%
and
a
specificity
of
82
%
for
confirmed
GAS
infection
.
The
emm
genotypes
in
21
GAS
isolates
from
children
with
pharyngitis
and
a
history
of
ARF
and
confirmed
RHD
were
emm
87
(
11
)
,
emm
12
(
6
)
,
emm
28
(
3
)
and
emm
5
(
1
)
.
This
study
demonstrates
a
very
high
prevalence
of
GAS
infections
in
Yemeni
children
and
the
value
of
the
RADT
and
the
McIsaac
score
in
this
setting
.
More
extensive
emm
genotyping
is
necessary
to
understand
the
local
epidemiology
of
circulating
strains
.
Diseases
Validation
Diseases presenting
"heart disease"
symptom
22q11.2 deletion syndrome
achondroplasia
acute rheumatic fever
adrenal incidentaloma
child syndrome
classical phenylketonuria
cohen syndrome
congenital diaphragmatic hernia
dentinogenesis imperfecta
esophageal adenocarcinoma
fabry disease
familial mediterranean fever
heparin-induced thrombocytopenia
hirschsprung disease
holt-oram syndrome
homocystinuria without methylmalonic aciduria
kabuki syndrome
monosomy 21
omenn syndrome
phenylketonuria
sneddon syndrome
systemic capillary leak syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom