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Prenatal education for congenital toxoplasmosis.
[congenital toxoplasmosis]
Congenital
toxoplasmosis
is
considered
a
rare
but
potentially
severe
infection
.
Prenatal
education
about
congenital
toxoplasmosis
could
be
the
most
efficient
and
least
harmful
intervention
,
yet
its
effectiveness
is
uncertain
.
To
assess
the
effects
of
prenatal
education
for
preventing
congenital
toxoplasmosis
.
We
searched
the
Cochrane
Pregnancy
and
Childbirth
Group
's
Trials
Register
(
15
January
2012
)
,
PubMed
(
1966
to
15
January
2012
)
,
EMBASE
(
1980
to
15
January
2012
)
,
CINAHL
(
1982
to
15
January
2012
)
,
LILACS
(
1982
to
15
January
2012
)
,
IMEMR
(
1984
to
15
January
2012
)
,
and
reference
lists
of
relevant
papers
,
reviews
and
websites
.
Randomized
and
quasi-randomized
controlled
trials
(
RCTs
)
of
all
types
of
prenatal
education
on
toxoplasmosis
infection
during
pregnancy
.
Cluster-randomized
trials
were
included
.
Two
review
authors
independently
assessed
trials
for
inclusion
and
study
quality
.
Two
review
authors
extracted
data
.
Data
were
checked
for
accuracy
.
Two
cluster-randomized
controlled
trials
(
involving
a
total
of
5455
women
)
met
the
inclusion
criteria
.
The
two
included
trials
measured
the
effectiveness
of
the
intervention
in
different
ways
which
meant
that
meta
-analysis
of
the
results
was
not
possible
One
trial
(
432
women
enrolled
)
conducted
in
Canada
was
judged
of
low
methodological
quality
.
The
authors
did
not
report
measure
of
association
but
only
provided
P
values
(
P
less
than
0
.
05
)
for
all
outcomes
.
Moreover
,
losses
to
follow-up
were
high
(
34
%
,
147
out
of
432
women
initially
enrolled
)
.
The
authors
concluded
that
prenatal
education
can
effectively
change
pregnant
women
's
behavior
as
it
increased
pet
,
personal
and
food
hygiene
.
The
second
trial
conducted
in
France
was
also
judged
of
low
methodological
quality
.
Losses
to
follow-up
were
high
(
44
.
5
%
,
2233
out
of
5023
women
initially
enrolled
)
and
differential
(
40
%
in
the
intervention
group
and
52
%
in
the
control
group
)
.
The
authors
concluded
that
prenatal
education
for
congenital
toxoplasmoses
has
a
significant
effect
on
improving
women
's
knowledge
whereas
it
has
no
effect
on
changing
women
's
behavior
.
In
this
trial
17
/
3949
pregnant
women
seroconverted
for
toxoplasmosis
:
13
/
2591
(
0
.
5
%
)
in
the
intervention
group
and
4
/
1358
(
0
.
3
%
)
in
the
control
group
.
The
number
of
events
was
too
small
to
reach
conclusions
about
the
effect
of
prenatal
education
on
seroconversion
rate
during
pregnancy
.
No
other
randomized
trials
on
the
effect
of
prenatal
education
on
congenital
toxoplasmosis
rate
,
or
toxoplasmosis
seroconversion
rate
during
pregnancy
were
detected
.
Even
though
primary
prevention
of
congenital
toxoplasmosis
is
considered
a
desirable
intervention
,
given
the
lack
of
related
risks
compared
to
secondary
and
tertiary
prevention
,
its
effectiveness
has
not
been
adequately
evaluated
.
There
is
very
little
evidence
from
RCTs
that
prenatal
education
is
effective
in
reducing
congenital
toxoplasmosis
even
though
evidence
from
observational
studies
suggests
it
is
.
Given
the
lack
of
good
evidence
supporting
prenatal
education
for
congenital
toxoplasmosis
prevention
,
further
RCTs
are
needed
to
confirm
any
potential
benefits
and
to
further
quantify
the
impact
of
different
sets
of
educational
intervention
.
Diseases
Validation
Diseases presenting
"potentially severe infection"
symptom
congenital toxoplasmosis
You can validate or delete this automatically detected symptom
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