Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Spinal Cord Lesions in Congenital Toxoplasmosis Demonstrated with Neuroimaging, Including Their Successful Treatment in an Adult.
[congenital toxoplasmosis]
Neuroimaging
studies
for
persons
in
the
National
Collaborative
Chicago
-
Based
Congenital
Toxoplasmosis
Study
(
NCCCTS
)
with
symptoms
and
signs
referable
to
the
spinal
cord
were
reviewed
.
Three
infants
had
symptomatic
spinal
cord
lesions
,
another
infant
a
Chiari
malformation
,
and
another
infant
a
symptomatic
peri-
spinal
cord
lipoma
.
One
patient
had
an
unusual
history
of
prolonged
spinal
cord
symptoms
presenting
in
middle
age
.
Neuroimaging
was
used
to
establish
her
diagnosis
and
response
to
treatment
.
This
43
year
-old
woman
with
congenital
toxoplasmosis
developed
progressive
leg
spasticity
,
weakness
,
numbness
,
difficulty
walking
,
and
decreased
visual
acuity
and
color
vision
without
documented
re
-activation
of
her
chorioretinal
disease
.
At
52
years
of
age
,
spinal
cord
lesions
in
locations
correlating
with
her
symptoms
and
optic
atrophy
were
diagnosed
with
3
Tesla
MRI
scan
.
Treatment
with
pyrimethamine
and
sulfadiazine
decreased
her
neurologic
symptoms
,
improved
her
neurologic
examination
,
and
resolved
her
enhancing
spinal
cord
lesions
seen
on
MRI
.
Diseases
Validation
Diseases presenting
"difficulty walking"
symptom
congenital toxoplasmosis
This symptom has already been validated