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Isolation of Toxoplasma gondii strains similar to Africa 1 genotype in Turkey.
[congenital toxoplasmosis]
Toxoplasma
gondii
is
a
protozoon
parasite
that
has
a
worldwide
dissemination
.
It
can
cause
serious
clinical
problems
such
as
congenital
toxoplasmosis
,
retinochoroiditis
,
and
encephalitis
.
Currently
,
T
.
gondii
genotypes
are
being
associated
with
these
clinical
presentations
which
may
help
clinicians
design
their
treatment
strategy
.
Two
T
.
gondii
strains
named
Ankara
and
Ege-
1
were
isolated
from
newborns
with
congenital
toxoplasmosis
in
Central
and
Western
Anatolia
,
respectively
.
Ankara
and
Ege-
1
strains
were
isolated
from
the
cerebrospinal
fluid
of
newborns
.
According
to
microsatellite
analysis
,
Ankara
and
Ege-
1
strains
were
sorted
as
Africa
1
genotype
.
T
.
gondii
strains
isolated
in
Turkey
were
first
time
genotyped
in
this
study
.
Africa
1
genotype
has
previously
been
isolated
in
immunosuppressed
patients
originating
from
sub-
Saharan
Africa
.
The
reason
of
detecting
a
strain
mainly
detected
in
Africa
can
be
associated
with
Turkey
's
specific
geographical
location
.
Turkey
is
like
a
bridge
between
Asia
,
Europe
and
Africa
.
Historically
,
Anatolia
was
on
the
Silk
Road
and
other
trading
routes
that
ended
in
Europe
.
Thus
,
detecting
Africa
1
strain
in
Anatolia
can
be
anticipated
.
Consequently
,
strains
detected
mainly
in
Europe
and
Asia
may
also
be
detected
in
Anatolia
and
vice
versa
.
Therefore
,
further
studies
are
required
to
isolate
more
strains
from
Turkey
.
Diseases
Validation
Diseases presenting
"sub-saharan africa"
symptom
congenital toxoplasmosis
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