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Seroprevalence of Anti-Toxoplasma gondii Antibodies Among Pregnant Woman in South Khuzestan, Iran.
[congenital toxoplasmosis]
Acute
toxoplasmosis
may
lead
to
congenital
toxoplasmosis
with
fetal
complications
outcome
during
pregnancy
.
Anti-
Toxoplasma
gondii
antibody
seroprevalence
is
unclear
in
pregnant
women
of
south
of
Khuzestan
province
,
since
limited
data
about
T
.
gondii
seroepidemiology
has
been
published
in
pregnant
women
of
this
area
(
Abadan
,
Shadegan
,
Khoramshar
)
.
The
aim
of
this
study
was
to
clarify
the
status
of
T
.
gondii
seroprevalence
in
pregnant
women
of
south
of
Khuzestan
province
.
In
this
cross-sectional
study
,
501
full-term
pregnant
women
were
included
.
This
study
was
carried
out
in
Taleghani
teaching
hospital
for
six
6
months
from
May
to
October
2011
.
Informed
consents
signed
by
the
patients
were
obtained
.
Blood
IgG
and
IgM
were
measured
using
ELISA
technique
.
The
data
was
analyzed
by
SPSS
13
(
Chicago
,
IL
,
USA
)
.
Chi
-square
test
was
used
for
comparison
.
The
participants
'
age
range
was
15
to
45
years
(
average
:
27
.
4
±
13
)
.
Of
the
501
pregnant
women
,
70
.
65
%
(
n
=
354
)
were
seronegative
for
T
.
gondii
IgG
and
IgM
antibodies
.
There
were
statistical
relationships
between
IgG
seroprevalence
and
age
,
as
well
as
IgG
seroprevalence
and
cat
holding
.
There
was
high
percentage
of
seronegative
(
70
.
65
%
)
IgG
and
IgM
antibodies
in
full-term
pregnant
women
.
They
were
susceptible
to
acute
toxoplasmosis
;
thus
,
prenatal
screening
was
recommend
in
our
province
after
cost-beneficial
analyses
.
Diseases
Validation
Diseases presenting
"fetal complications outcome"
symptom
congenital toxoplasmosis
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