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Acute rheumatic fever and rheumatic heart disease in the Kimberley: using hospitalisation data to find cases and describe trends.
[acute rheumatic fever]
Objective
:
To
describe
the
epidemiology
of
hospitalisations
due
to
acute
rheumatic
fever
(
ARF
)
and
rheumatic
heart
disease
(
RHD
)
in
the
Kimberley
region
of
Western
Australia
(
WA
)
and
use
these
data
to
improve
completeness
of
the
WA
RHD
Register
.
Methods
:
Retrospective
analysis
of
Kimberley
regional
hospitalisation
data
for
hospitalisations
coded
as
ARF
/
RHD
from
01
/
07
/
2002
to
30
/
06
/
2012
,
with
individual
follow-up
of
those
not
on
the
register
.
Annual
age-standardised
hospitalisation
rates
were
calculated
to
determine
hospitalisation
trend
.
Results
:
There
were
250
admissions
among
193
individuals
.
Of
these
,
53
individuals
(
27
%
)
with
confirmed
or
probable
ARF
/
RHD
were
not
on
the
register
.
Males
were
less
likely
to
be
on
the
register
(
62
%
versus
79
%
of
females
,
p
<
0
.
01
)
,
as
were
those
hospitalised
with
ARF
without
heart
involvement
(
68
%
versus
87
%
of
other
ARF
diagnoses
,
p
<
0
.
01
)
.
ARF
/
RHD
hospitalisation
rates
decreased
by
8
.
8
%
per
year
(
p
<
0
.
001
,
rate
ratio
=
0
.
91
,
95
%
CI
0
.
87
-
0
.
96
)
.
Conclusions
and
implications
:
Using
hospitalisation
data
is
an
effective
method
of
identifying
cases
of
ARF
/
RHD
not
currently
on
the
register
.
This
process
could
be
undertaken
for
initial
case
finding
in
areas
with
newly
established
registers
,
or
as
regular
quality
assurance
in
areas
with
established
register-based
programs
.
Reasons
for
the
observed
decrease
in
hospitalisation
rates
remain
unclear
and
warrant
further
investigation
.
Diseases
Validation
Diseases presenting
"heart disease"
symptom
22q11.2 deletion syndrome
achondroplasia
acute rheumatic fever
adrenal incidentaloma
child syndrome
classical phenylketonuria
cohen syndrome
congenital diaphragmatic hernia
dentinogenesis imperfecta
esophageal adenocarcinoma
fabry disease
familial mediterranean fever
heparin-induced thrombocytopenia
hirschsprung disease
holt-oram syndrome
homocystinuria without methylmalonic aciduria
kabuki syndrome
monosomy 21
omenn syndrome
phenylketonuria
sneddon syndrome
systemic capillary leak syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
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