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Animals are key to human toxoplasmosis.
[congenital toxoplasmosis]
Toxoplasma
gondii
is
an
extremely
sucessfull
protozoal
parasite
which
infects
almost
all
mamalian
species
including
humans
.
Approximately
30
%
of
the
human
population
worldwide
is
chronically
infected
with
T
.
gondii
.
In
general
,
human
infection
is
asymptomatic
but
the
parasite
may
induce
severe
disease
in
fetuses
and
immunocompromised
patients
.
In
addition
,
T
.
gondii
may
cause
sight-threatening
posterior
uveitis
in
immunocompetent
patients
.
Apart
from
few
exceptions
,
humans
acquire
T
.
gondii
from
animals
.
Both
,
the
oral
uptake
of
T
.
gondii
oocysts
released
by
specific
hosts
,
i
.
e
.
felidae
,
and
of
cysts
persisting
in
muscle
cells
of
animals
result
in
human
toxoplasmosis
.
In
the
present
review
,
we
discuss
recent
new
data
on
the
cell
biology
of
T
.
gondii
and
parasite
diversity
in
animals
.
In
addition
,
we
focus
on
the
impact
of
these
various
parasite
strains
and
their
different
virulence
on
the
clinical
outcome
of
human
congenital
toxoplasmosis
and
T
.
gondii
uveitis
.
Diseases
Validation
Diseases presenting
"recent new data on the cell biology"
symptom
congenital toxoplasmosis
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