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Predictors of low weight and tube feedings in children with congenital diaphragmatic hernia at 1 year of age.
[congenital diaphragmatic hernia]
Congenital
diaphragmatic
hernia
(
CDH
)
survivors
often
have
gastrointestinal
disorders
,
and
limited
outcome
data
exist
.
This
study
reviewed
risk
factors
for
low
weight
and
use
of
feeding
tubes
after
CDH
repair
at
1
year
of
age
.
The
hypothesis
was
that
patients
who
required
extracorporeal
membrane
oxygenation
(
ECMO
)
or
with
significant
pulmonary
arterial
hypertension
(
PAH
)
would
have
lower
weight
percentiles
and
more
often
require
tube
feedings
.
A
retrospective
chart
review
of
89
infants
with
CDH
diagnosed
in
the
neonatal
period
was
conducted
.
Statistical
analysis
was
performed
using
χ
test
,
Fisher
exact
test
,
and
logistic
regression
.
Seventy
-
two
patients
(
81
%
)
survived
to
1
year
of
age
.
Of
these
patients
,
35
%
were
<
5
th
percentile
for
weight
and
18
%
were
receiving
tube
feedings
.
Both
ECMO
and
PAH
were
associated
with
an
increased
risk
for
requiring
tube
feedings
at
1
year
of
age
,
with
respective
odds
ratios
of
6
.
00
(
P
=
0
.
01
)
and
15
.
75
(
P
=
0
.
02
)
;
however
,
neither
ECMO
nor
PAH
was
associated
with
low
weight
at
1
year
of
age
.
No
statistical
correlation
was
found
between
an
abnormal
pH
probe
and
tube
feedings
at
1
year
of
age
.
Patients
with
CDH
are
at
increased
risk
for
having
a
weight
<
5
th
percentile
at
1
year
of
age
.
A
history
of
ECMO
and
PAH
are
independently
associated
with
an
increased
requirement
for
tube
feedings
at
1
year
of
age
.
Close
nutritional
monitoring
and
counseling
should
be
considered
in
all
of
the
patients
with
CDH
,
particularly
those
with
a
history
of
ECMO
or
PAH
.
Diseases
Validation
Diseases presenting
"significant pulmonary arterial hypertension"
symptom
congenital diaphragmatic hernia
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