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Prognostic usefulness of derived T2-weighted fetal magnetic resonance imaging measurements in congenital diaphragmatic hernia.
[congenital diaphragmatic hernia]
To
determine
the
usefulness
of
various
parameters
based
on
T
2
-
weighted
fetal
magnetic
resonance
(
MR
)
imaging
measurements
of
the
uninvolved
lung
for
the
neonatal
prognosis
of
congenital
diaphragmatic
hernia
(
CDH
)
.
We
used
ultrasonography
and
MR
imaging
to
study
28
fetuses
with
CDH
.
We
retrospectively
analyzed
a
)
on
fetal
ultrasonography
,
the
observed
-
to
-expected
lung
to
head
ratio
(
O
/
E
LHR
)
and
the
position
of
the
liver
,
and
b
)
on
fetal
MR
imaging
,
the
lung
-
liver
signal
ratio
(
LLSR
)
and
the
lungcerebrospinal
fluid
ratio
(
L
/
CSF
SR
)
.
To
determine
the
prognostic
value
of
these
parameters
,
we
compared
them
with
the
following
postnatal
parameters
:
survival
,
pulmonary
hypertension
,
need
for
oxygen
supplementation
,
and
need
for
extracorporeal
membrane
oxygenation
.
We
found
significant
differences
between
O
/
E
LHR
and
the
need
for
postnatal
extracorporeal
membrane
oxygenation
(
P
=
.
033
)
and
postnatal
survival
(
P
=
.
01
)
.
We
also
found
significant
differences
in
LLSR
between
fetuses
that
survived
more
than
45
days
and
those
that
died
within
45
days
(
1
.
91
vs
.
2
.
56
;
P
=
.
039
)
.
In
fetuses
with
CDH
,
the
LLSR
correlates
with
postnatal
survival
and
can
potentially
be
used
as
a
prognostic
parameter
in
CDH
.
Diseases
Validation
Diseases presenting
"postnatal parameters"
symptom
congenital diaphragmatic hernia
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