Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Inhaled nitric oxide use in neonates with congenital diaphragmatic hernia.
[congenital diaphragmatic hernia]
To
describe
the
use
of
inhaled
nitric
oxide
(
INO
)
in
newborns
with
congenital
diaphragmatic
hernia
(
CDH
)
.
Pediatric
Health
Information
System
data
were
queried
for
newborns
with
CDH
admitted
at
<
8
days
of
age
at
tertiary
care
US
pediatric
hospitals
between
2003
and
2011
.
INO
treatment
status
and
timing
in
relation
to
CDH
repair
were
determined
for
each
infant
.
Hospital
-
specific
rates
of
INO
use
,
extracorporeal
membrane
oxygenation
(
ECMO
)
use
,
and
mortality
were
determined
.
Data
were
analyzed
for
1713
neonates
with
CDH
admitted
to
33
hospitals
.
More
than
half
(
57
%
)
received
INO
during
their
inpatient
stay
,
and
utilization
varied
dramatically
between
hospitals
(
34
%
to
92
%
)
.
Neonates
treated
with
INO
accumulated
>
$
81
million
in
pharmacy
charges
.
The
proportion
of
infants
receiving
INO
as
well
as
their
duration
of
therapy
increased
significantly
during
the
study
period
.
The
rate
of
ECMO
utilization
and
mortality
did
not
change
significantly
during
the
study
period
.
Hospital
-
specific
mortality
rates
did
not
correlate
with
INO
therapy
,
ECMO
utilization
,
or
case
volume
.
INO
use
in
neonates
with
CDH
is
widespread
,
and
has
increased
at
many
US
tertiary
pediatric
hospitals
without
contemporaneous
change
in
ECMO
utilization
or
mortality
.
The
improvement
of
evidence-based
guidelines
for
the
use
of
INO
in
newborns
with
CDH
could
lead
to
a
reduction
in
health
care
costs
for
these
patients
.
Diseases
Validation
Diseases presenting
"reduction in health care costs for these patients"
symptom
congenital diaphragmatic hernia
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom