Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia: indications, outcomes, and future directions.
[congenital diaphragmatic hernia]
In
the
present
study
,
we
review
the
indications
,
technical
aspects
,
preliminary
results
,
risks
,
and
clinical
implications
of
fetal
endoscopic
tracheal
occlusion
(
FETO
)
for
severe
congenital
diaphragmatic
hernia
(
CDH
)
performed
outside
the
United
States
and
its
potential
future
directions
in
this
country
and
globally
.
Congenital
diaphragmatic
hernia
occurs
in
approximately
1
in
2500
live
births
and
results
in
high
neonatal
morbidity
and
mortality
,
largely
associated
with
the
severity
of
pulmonary
hypoplasia
and
pulmonary
arterial
hypertension
.
With
the
advent
of
prenatal
imaging
,
CDH
can
be
diagnosed
before
birth
,
and
in
utero
treatment
is
now
available
in
some
centers
.
The
prognosis
of
CDH
can
be
evaluated
by
assessing
the
fetal
lung
size
,
the
degree
of
liver
herniation
,
and
the
fetal
pulmonary
vasculature
in
isolated
forms
of
CDH
.
These
parameters
help
classify
fetuses
as
having
mild
,
moderate
,
severe
,
or
extremely
severe
isolated
CDH
.
Severe
and
extremely
severe
diaphragmatic
hernias
have
poor
outcomes
and
thus
are
candidates
for
innovative
therapies
such
as
FETO
.
Fetal
endoscopic
tracheal
occlusion
is
usually
performed
between
26
and
30
weeks
'
gestation
.
In
utero
,
an
endoscope
is
passed
through
the
fetal
mouth
and
down
to
the
carina
;
the
balloon
is
deployed
just
above
the
carina
.
After
the
procedure
,
ultrasound
surveillance
every
2
weeks
ensures
the
balloon
's
structural
integrity
and
measures
the
fetal
pulmonary
response
.
At
approximately
34
weeks
'
gestation
,
the
balloon
is
deflated
and
removed
.
Fetal
endoscopic
tracheal
occlusion
is
thought
to
improve
outcomes
by
decreasing
mortality
and
allowing
more
rapid
neonatal
stabilization
.
Ultimately
,
the
goal
of
FETO
is
to
minimize
pulmonary
hypoplasia
and
pulmonary
arterial
hypertension
.
Following
delivery
,
neonates
still
require
diaphragm
repair
.
Diseases
Validation
Diseases presenting
"thus are candidates for innovative therapies such as feto"
symptom
congenital diaphragmatic hernia
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom