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Growth in children with congenital diaphragmatic hernia during the first year of life.
[congenital diaphragmatic hernia]
Infants
with
congenital
diaphragmatic
hernia
(
CDH
)
have
high
rates
of
mortality
and
long
-term
morbidity
,
including
poor
growth
and
failure
to
thrive
.
The
aim
of
this
study
was
to
describe
growth
patterns
during
the
first
year
of
life
in
infants
with
congenital
diaphragmatic
hernia
in
a
non-
ECMO
cohort
.
Medical
records
of
infants
with
CDH
admitted
to
our
center
between
January
2005
and
December
2011
were
reviewed
.
Infants
with
anthropometric
measurements
at
3
,
6
and
12
months
were
included
.
Anthropometric
measurements
were
obtained
for
the
first
year
of
life
.
Logistic
regression
analyses
were
performed
to
find
predictive
associations
with
failure
to
thrive
(
FTT
)
.
Of
the
45
survivors
,
38
were
seen
twice
(
84
%
)
and
24
(
53
%
)
were
seen
on
three
occasions
to
age
12
months
.
Poor
growth
was
observed
with
weight
being
most
affected
.
FTT
was
present
in
63
%
during
the
first
six
months
of
life
.
Days
of
mechanical
ventilation
were
the
only
predictor
of
FTT
.
Besides
poor
weight
gain
,
height
and
head
circumference
were
also
reduced
.
However
,
catch-up
growth
occurred
during
the
second
half
of
infancy
and
at
age
12
months
failure
to
thrive
had
reduced
by
two
thirds
to
21
%
.
Poor
growth
is
a
common
early
finding
in
CDH
patients
,
which
improves
during
infancy
.
This
emphasizes
the
importance
of
close
follow-up
and
aggressive
nutritional
management
in
CDH
patients
.
Diseases
Validation
Diseases presenting
"failure to thrive"
symptom
22q11.2 deletion syndrome
alexander disease
child syndrome
congenital diaphragmatic hernia
cystinuria
familial hypocalciuric hypercalcemia
hirschsprung disease
homocystinuria without methylmalonic aciduria
junctional epidermolysis bullosa
kabuki syndrome
kindler syndrome
krabbe disease
neonatal adrenoleukodystrophy
omenn syndrome
papillon-lefèvre syndrome
pyruvate dehydrogenase deficiency
triple a syndrome
wolf-hirschhorn syndrome
zellweger syndrome
This symptom has already been validated