Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
[Congenital adrenal hyperplasia in the adult women: management of old and new challenges].
[congenital adrenal hyperplasia]
Due
to
major
improvements
in
the
management
and
therapy
of
patients
with
congenital
adrenal
hyperplasia
owing
to
21
-
hydroxylase
deficiency
(
21
OHD
)
along
childhood
and
adolescence
,
affected
women
are
able
to
reach
adulthood
.
Therefore
,
management
throughout
adult
life
became
even
more
complex
,
leading
to
new
challenges
.
Both
the
protracted
use
of
corticosteroids
(
sometimes
in
supraphysiologic
doses
)
,
and
excess
androgen
(
due
to
irregular
treatment
and
/
or
inadequate
dosage
)
may
impair
the
quality
of
life
and
health
outcomes
in
affected
adult
women
,
causing
osteoporosis
,
metabolic
disturbances
with
high
cardiovascular
risk
,
cosmetic
damage
,
infertility
,
and
psychosocial
and
psychosexual
changes
.
However
,
long
-term
follow-up
studies
with
21
OHD
adult
women
are
still
required
.
In
this
review
,
we
discuss
some
important
and
controversial
aspects
of
the
follow-up
of
adult
women
with
21
OHD
,
and
recommend
the
use
of
a
customized
multi-disciplinary
therapeutic
approach
while
further
studies
with
these
patients
do
not
provide
distinct
understanding
and
well-defined
attitudes
towards
better
quality
of
life
.
Diseases
Validation
Diseases presenting
"affected adult women, causing osteoporosis"
symptom
congenital adrenal hyperplasia
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom