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Increased Prevalence of Testicular Adrenal Rest Tumours during Adolescence in Congenital Adrenal Hyperplasia.
[congenital adrenal hyperplasia]
Testicular
adrenal
rest
tumours
(
TART
)
are
one
of
the
most
important
causes
of
infertility
in
adult
male
patients
with
congenital
adrenal
hyperplasia
(
CAH
)
.
These
benign
tumours
are
already
detected
in
children
,
but
screening
of
TART
is
not
routinely
performed
.
To
define
retrospectively
the
prevalence
of
TART
in
41
paediatric
male
CAH
patients
aged
0
-
19
years
regularly
followed
by
high
-frequency
(
Fcentral
12
-
MHz
)
ultrasound
techniques
.
Above
the
age
of
10
years
,
there
was
a
clear
increase
in
the
prevalence
of
TART
:
10
-
12
years
,
28
%
(
2
of
7
patients
)
,
13
-
14
years
,
50
%
(
4
/
8
)
,
and
15
-
16
years
,
75
%
(
3
/
4
)
.
Above
the
age
of
16
years
,
TART
were
detected
in
100
%
of
the
patients
(
7
/
7
)
.
The
tumours
were
not
detectable
by
palpation
.
TART
is
already
present
in
childhood
with
an
increasing
prevalence
after
onset
of
puberty
.
We
recommend
regular
ultrasound
from
the
onset
of
puberty
in
all
boys
with
classic
CAH
.
©
2014
S
.
Karger
AG
,
Basel
.
