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Between scylla and charybdis: a bleomycin-exposed patient with Cohen syndrome.
[cohen syndrome]
Chemotherapy
with
bleomycin
may
cause
a
syndrome
of
pulmonary
sensitivity
to
supranormal
inspired
oxygen
concentrations
that
persists
for
an
unknown
period
of
time
after
exposure
.
We
present
a
mentally
retarded
adolescent
patient
in
whom
supranormal
inspired
oxygen
was
temporarily
necessary
to
manage
her
difficult
airway
.
Subsequently
her
pulmonary
function
deteriorated
acutely
and
,
after
intermittent
stabilization
,
irreversibly
.
In
this
case
,
bleomycin
exposure
may
have
played
a
pivotal
role
in
modulating
minor
insults
to
trigger
fatal
acute
respiratory
distress
syndrome
(
ARDS
)
.
Diseases
Validation
Diseases presenting
"pulmonary function"
symptom
allergic bronchopulmonary aspergillosis
cohen syndrome
congenital diaphragmatic hernia
inclusion body myositis
lymphangioleiomyomatosis
systemic capillary leak syndrome
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