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Glial tumors of the retina. The 2009 King Khaled Memorial Lecture.
[coats disease]
Retinal
glial
tumors
and
pseudotumors
can
be
classified
into
astrocytic
hamartoma
,
acquired
retinal
astrocytoma
,
massive
gliosis
,
and
focal
nodular
gliosis
.
Each
has
different
clinical
manifestations
.
Astrocytic
hamartoma
is
usually
seen
patients
who
have
some
manifestations
of
tuberous
sclerosis
complex
(
TSC
)
.
It
can
occur
as
a
noncalcified
or
calcified
variety
,
and
often
a
combination
of
the
two
,
and
has
fairly
typical
features
with
fluorescein
angiography
,
ultrasonography
,
and
optical
coherence
tomography
.
Although
it
is
generally
a
stationary
lesion
,
an
aggressive
variant
seen
in
very
young
children
with
TSC
can
lead
to
exudative
retinopathy
,
retinal
detachment
,
and
neovascular
glaucoma
.
Acquired
astrocytoma
general
occurs
in
somewhat
older
individuals
who
do
not
have
TSC
.
Like
the
aggressive
form
of
astrocytic
hamartoma
it
can
lead
to
exudative
retinopathy
and
exudative
retinal
detachment
.
Pseudoneoplastic
diffuse
retinal
gliosis
can
occur
as
massive
glial
proliferation
in
eyes
with
prior
trauma
,
Coats
disease
,
retinal
angiomatosis
and
other
conditions
and
often
occurs
in
blind
eyes
.
Pseudoneoplastic
focal
retinal
gliosis
is
characterized
by
a
very
superficial
,
white
,
noncalcified
lesion
in
otherwise
normal
eye
in
somewhat
older
individuals
.
Recognition
of
these
glial
lesions
is
important
because
they
can
resemble
malignant
tumors
and
have
different
clinical
courses
and
complications
.
Diseases
Validation
Diseases presenting
"retinal glial tumors"
symptom
coats disease
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