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Glial tumors of the retina. The 2009 King Khaled Memorial Lecture.
[coats disease]
Retinal
glial
tumors
and
pseudotumors
can
be
classified
into
astrocytic
hamartoma
,
acquired
retinal
astrocytoma
,
massive
gliosis
,
and
focal
nodular
gliosis
.
Each
has
different
clinical
manifestations
.
Astrocytic
hamartoma
is
usually
seen
patients
who
have
some
manifestations
of
tuberous
sclerosis
complex
(
TSC
)
.
It
can
occur
as
a
noncalcified
or
calcified
variety
,
and
often
a
combination
of
the
two
,
and
has
fairly
typical
features
with
fluorescein
angiography
,
ultrasonography
,
and
optical
coherence
tomography
.
Although
it
is
generally
a
stationary
lesion
,
an
aggressive
variant
seen
in
very
young
children
with
TSC
can
lead
to
exudative
retinopathy
,
retinal
detachment
,
and
neovascular
glaucoma
.
Acquired
astrocytoma
general
occurs
in
somewhat
older
individuals
who
do
not
have
TSC
.
Like
the
aggressive
form
of
astrocytic
hamartoma
it
can
lead
to
exudative
retinopathy
and
exudative
retinal
detachment
.
Pseudoneoplastic
diffuse
retinal
gliosis
can
occur
as
massive
glial
proliferation
in
eyes
with
prior
trauma
,
Coats
disease
,
retinal
angiomatosis
and
other
conditions
and
often
occurs
in
blind
eyes
.
Pseudoneoplastic
focal
retinal
gliosis
is
characterized
by
a
very
superficial
,
white
,
noncalcified
lesion
in
otherwise
normal
eye
in
somewhat
older
individuals
.
Recognition
of
these
glial
lesions
is
important
because
they
can
resemble
malignant
tumors
and
have
different
clinical
courses
and
complications
.
Diseases
Validation
Diseases presenting
"malignant tumors"
symptom
adrenal incidentaloma
cholangiocarcinoma
coats disease
cowden syndrome
cushing syndrome
dedifferentiated liposarcoma
dentinogenesis imperfecta
esophageal carcinoma
focal myositis
junctional epidermolysis bullosa
liposarcoma
pleomorphic liposarcoma
von hippel-lindau disease
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