Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Diagnosis of retinoblastoma: how good are referring physicians?
[coats disease]
To
evaluate
accuracy
of
the
referring
diagnoses
of
retinoblastoma
to
a
tertiary
cancer
referral
center
.
Retrospective
chart
review
of
352
retinoblastoma
-related
patients
seen
by
the
ophthalmic
oncology
service
during
a
4
-
year
period
from
January
1
,
2004
to
October
21
,
2008
.
Of
these
,
111
were
referred
with
a
suspicion
of
new
retinoblastoma
and
were
included
in
the
study
.
Fundus
photographs
,
gender
,
family
history
of
retinoblastoma
,
initial
symptoms
,
age
,
initial
and
referring
physicians
'
specialty
(
eg
,
pediatrician
,
general
ophthalmologist
,
retinal
specialist
)
and
their
suspected
diagnoses
were
recorded
.
The
main
outcome
measure
was
accuracy
of
diagnosis
given
by
referring
providers
.
Of
111
patients
,
62
%
had
retinoblastoma
and
38
%
did
not
.
Persistent
fetal
vasculature
(
PFV
)
and
Coats
'
Disease
were
the
most
common
simulating
lesions
accounting
for
31
%
and
29
%
of
the
simulating
lesions
respectively
.
Other
simulating
lesions
included
infrequent
cases
of
rare
conditions
such
as
primary
ocular
teratoma
,
a
retinal
pigment
epithelial
tumor
,
and
astrocytic
hamartoma
.
Retinoblastoma
continues
to
present
a
diagnostic
dilemma
.
There
has
been
limited
improvement
in
the
rate
of
correct
diagnosis
in
the
United
States
in
the
last
15
years
.
There
has
however
been
a
change
in
the
composition
of
misdiagnosed
lesions
with
rare
conditions
accounting
for
more
than
1
/
3
of
cases
.
Attention
to
age
,
family
history
,
laterality
and
presenting
signs
such
as
globe
size
can
aid
diagnosis
of
retinoblastoma
.
Diseases
Validation
Diseases presenting
"were included in the study"
symptom
coats disease
heparin-induced thrombocytopenia
You can validate or delete this automatically detected symptom
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