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RETINAL ANGIOMATOUS PROLIFERATION WITH CHORIORETINAL ANASTOMOSIS IN CHILDHOOD COATS DISEASE: A Reappraisal of Macular Fibrosis Using Multimodal Imaging.
[coats disease]
To
describe
the
structural
characteristics
of
retinal
angiomatous
proliferation
and
chorioretinal
anastomosis
in
childhood
Coats
disease
and
redefine
the
previously
described
macular
fibrosis
.
Prospective
observational
case
series
of
consecutive
patients
with
Coats
disease
examined
over
a
1
-
year
study
period
.
Multimodal
imaging
,
including
color
fundus
photography
,
wide
-field
fluorescein
angiography
,
and
spectral
domain
optical
coherence
tomography
,
was
used
to
identify
the
features
of
macular
retinal
angiomatous
proliferation
and
chorioretinal
anastomosis
.
Retinal
angiomatous
proliferation
and
chorioretinal
anastomosis
were
present
in
5
of
21
patients
with
Coats
disease
(
24
%
)
.
The
lesions
appeared
as
well
demarcated
,
nodular
retinal
pigment
epithelial
detachments
surrounded
by
exudate
,
with
retinal
vessels
continuous
with
the
underlying
choroidal
neovascularization
.
Retinal
angiomatous
proliferation
and
chorioretinal
anastomoses
are
features
observed
in
a
number
of
children
(
24
%
in
the
present
series
)
with
Coats
disease
and
macular
involvement
.
This
lesion
represents
a
distinct
macular
variant
of
Coats
disease
that
underlies
at
least
a
proportion
(
all
in
the
present
series
)
of
the
previously
described
"
macular
fibrosis
"
and
"
subretinal
mounds
.
"
Diseases
Validation
Diseases presenting
"chorioretinal anastomosis in childhood coats disease and redefine the previously described macular fibrosis"
symptom
coats disease
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