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Reversible Cerebellar Ataxia Related to Extrapontine Myelinolysis without Hyponatremia after Cisplatin-Based Chemotherapy for Cholangiocarcinoma.
[cholangiocarcinoma]
A
60
-
year
-old
woman
presented
with
cerebellar
signs
including
dysarthria
and
ataxia
,
after
intravenous
infusion
of
cisplatin-based
chemotherapy
.
Several
blood
tests
showed
mild
neutropenia
,
normocytic
normochromic
anemia
,
but
no
evidence
of
a
marked
hyponatremia
.
Brain
magnetic
resonance
imaging
with
diffusion-weighted
sequences
showed
hyper-intense
signal
abnormalities
in
the
extrapontine
region
,
sparing
the
basis
pontis
.
Here
,
we
report
on
the
case
of
a
patient
with
reversible
cerebellar
ataxia
related
to
extrapontine
myelinolysis
without
hyponatremia
after
treatment
with
cisplatin-based
chemotherapy
for
cholangiocarcinoma
and
discuss
the
literature
on
cerebellar
ataxia
in
patients
who
underwent
recent
chemotherapy
for
malignancy
.
Diseases
Validation
Diseases presenting
"blood tests"
symptom
allergic bronchopulmonary aspergillosis
benign recurrent intrahepatic cholestasis
carcinoma of the gallbladder
cholangiocarcinoma
cushing syndrome
esophageal carcinoma
esophageal squamous cell carcinoma
lymphangioleiomyomatosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
systemic capillary leak syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
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