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Intraductal papillary neoplasm of the bile duct developing in a patient with primary sclerosing cholangitis: A case report.
[cholangiocarcinoma]
We
report
a
case
of
intraductal
papillary
neoplasm
of
the
bile
duct
(
IPNB
)
that
developed
in
a
patient
with
primary
sclerosing
cholangitis
.
A
46
-
year
-old
woman
was
admitted
to
our
hospital
with
obstructive
jaundice
.
The
liver
function
tests
demonstrated
increased
serum
liver
enzyme
levels
.
Computed
tomography
showed
dilatation
of
the
intrahepatic
bile
ducts
.
Abdominal
ultrasonography
revealed
a
highly
echoic
protruding
lesion
in
the
posterior
bile
duct
near
the
right
lobe
of
the
liver
.
The
lesion
was
suspected
to
be
IPNB
,
but
we
were
unable
to
confirm
whether
it
was
a
carcinoma
.
A
right
hepatectomy
was
performed
,
and
this
showed
that
the
dilated
bile
duct
was
filled
with
mucin
and
contained
several
yellowish
papillary
tumors
.
Histologically
,
the
neoplastic
biliary
epithelium
showed
papillary
growth
in
the
dilated
lumen
.
The
tumor
was
diagnosed
as
IPNB
,
high
-grade
intraepithelial
neoplasia
secreting
abundant
mucin
.
No
recurrence
has
been
detected
3
years
after
surgery
.