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Mucin-producing carcinoma of the gallbladder associated with primary sclerosing cholangitis and ulcerative colitis.
[carcinoma of the gallbladder]
Mucin-producing
carcinoma
of
the
gallbladder
is
very
rare
.
We
report
here
a
case
of
mucin-producing
carcinoma
of
the
gallbladder
associated
with
primary
sclerosing
cholangitis
(
PSC
)
and
ulcerative
colitis
(
UC
)
.
A
74
-
year
-old
female
had
been
treated
with
salazosulfapyridine
and
ursodesoxycholic
acid
becase
of
UC
and
PSC
.
After
7
years
of
treatment
,
laboratory
data
showed
that
the
liver
function
took
a
turn
for
the
worse
,
and
the
patient
was
admitted
to
our
hospital
for
further
examination
.
Enhanced
computed
tomography
and
ultrasonography
showed
an
enlarged
gallbladder
associated
with
wall
thickening
and
diffuse
papillary
protrusion
.
Endoscopic
retrograde
cholangiography
showed
stenosis
and
dilatation
of
the
bile
duct
,
which
were
compatible
with
PSC
.
Under
the
diagnosis
of
an
early
carcinoma
of
the
gallbladder
,
we
performed
simple
cholecystectomy
.
The
tumor
showed
a
papillary
growth
pattern
located
diffusely
in
the
gallbladder
with
a
massive
amount
of
mucin
filling
the
gallbladder
.
Histologically
,
it
was
diagnosed
as
a
papillary
adenocarcinoma
localized
in
the
mucosal
layer
.
To
the
best
of
our
knowledge
,
this
is
the
first
case
of
mucin-producing
carcinoma
of
the
gallbladder
associated
with
PSC
and
UC
.
PSC
and
UC
patients
should
be
regarded
as
a
high
-risk
group
not
only
for
cholangiocarcinoma
but
also
carcinoma
of
the
gallbladder
.
Diseases
Validation
Diseases presenting
"first case"
symptom
achondroplasia
adrenal incidentaloma
allergic bronchopulmonary aspergillosis
alpha-thalassemia
aniridia
aromatase deficiency
canavan disease
carcinoma of the gallbladder
child syndrome
cholangiocarcinoma
classical phenylketonuria
coats disease
cohen syndrome
congenital toxoplasmosis
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dentin dysplasia
dracunculiasis
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
esophageal adenocarcinoma
esophageal carcinoma
fabry disease
familial mediterranean fever
focal myositis
gm1 gangliosidosis
harlequin ichthyosis
hodgkin lymphoma, classical
homocystinuria without methylmalonic aciduria
junctional epidermolysis bullosa
kabuki syndrome
krabbe disease
lamellar ichthyosis
legionellosis
liposarcoma
locked-in syndrome
malignant atrophic papulosis
monosomy 21
neonatal adrenoleukodystrophy
oculocutaneous albinism
omenn syndrome
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
primary hyperoxaluria type 1
proteus syndrome
pyomyositis
systemic capillary leak syndrome
thoracic outlet syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
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