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Signet ring cell carcinoma of the gallbladder in a 22-year-old man: a case report and review of the literature.
[carcinoma of the gallbladder]
Primary
carcinoma
of
the
gallbladder
is
an
uncommon
malignancy
with
a
variable
incidence
among
different
geographic
locales
and
ethnic
groups
.
Women
are
affected
generally
3
times
as
often
as
men
.
Choleliths
are
a
significant
risk
factor
.
Other
risk
factors
include
abnormal
union
of
the
choledochopancreatic
ducts
,
obesity
,
multiparity
,
chronic
infection
with
certain
bacteria
,
and
genetics
.
The
signet
ring
cell
subtype
of
adenocarcinoma
is
a
rare
entity
.
The
behavior
of
this
subtype
is
not
well
described
in
the
literature
.
The
authors
present
a
case
of
signet
ring
cell
carcinoma
of
the
gallbladder
,
unusual
in
their
case
because
of
the
patient
's
young
age
,
male
gender
,
African
American
ethnicity
,
and
lack
of
choleliths
or
any
other
risk
factors
.
They
review
the
literature
in
English
to
characterize
this
rare
subtype
.
Diseases
Validation
Diseases presenting
"obesity"
symptom
acute rheumatic fever
adrenal incidentaloma
aniridia
aromatase deficiency
carcinoma of the gallbladder
cohen syndrome
congenital adrenal hyperplasia
cushing syndrome
cystinuria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
heparin-induced thrombocytopenia
kabuki syndrome
monosomy 21
phenylketonuria
primary hyperoxaluria type 1
sneddon syndrome
werner syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated