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Signet ring cell carcinoma of the gallbladder in a 22-year-old man: a case report and review of the literature.
[carcinoma of the gallbladder]
Primary
carcinoma
of
the
gallbladder
is
an
uncommon
malignancy
with
a
variable
incidence
among
different
geographic
locales
and
ethnic
groups
.
Women
are
affected
generally
3
times
as
often
as
men
.
Choleliths
are
a
significant
risk
factor
.
Other
risk
factors
include
abnormal
union
of
the
choledochopancreatic
ducts
,
obesity
,
multiparity
,
chronic
infection
with
certain
bacteria
,
and
genetics
.
The
signet
ring
cell
subtype
of
adenocarcinoma
is
a
rare
entity
.
The
behavior
of
this
subtype
is
not
well
described
in
the
literature
.
The
authors
present
a
case
of
signet
ring
cell
carcinoma
of
the
gallbladder
,
unusual
in
their
case
because
of
the
patient
's
young
age
,
male
gender
,
African
American
ethnicity
,
and
lack
of
choleliths
or
any
other
risk
factors
.
They
review
the
literature
in
English
to
characterize
this
rare
subtype
.
