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Early gallbladder carcinoma: a clinicopathologic study of 13 cases of intramucosal carcinoma.
[carcinoma of the gallbladder]
We
report
the
clinicopathologic
features
of
13
cases
of
intramucosal
carcinoma
(
IMC
)
of
the
gallbladder
.
All
IMCs
were
incidental
findings
in
cholecystectomy
specimens
for
cholelithiasis
.
However
,
one
of
the
patients
had
a
carcinoma
of
the
pancreas
,
and
the
gallbladder
incidentally
removed
during
the
Whipple
procedure
showed
an
IMC
.
Another
patient
had
a
small
cell
carcinoma
of
the
gallbladder
,
and
one
of
the
sections
showed
an
IMC
.
Of
the
IMCs
,
10
were
well-differentiated
adenocarcinomas
,
1
was
a
moderately
differentiated
adenocarcinoma
,
1
was
an
undifferentiated
carcinoma
,
and
1
was
a
squamous
cell
carcinoma
.
Of
the
patients
,
8
were
disease-free
from
3
to
11
years
,
and
2
patients
died
,
one
as
a
result
of
the
pancreatic
ductal
carcinoma
and
the
other
with
disseminated
metastases
of
the
small
cell
carcinoma
.
The
follow-up
of
another
patient
was
too
short
to
be
significant
.
Two
patients
were
lost
to
follow-up
.
Our
findings
suggest
that
a
simple
cholecystectomy
is
a
curative
procedure
for
IMCs
of
the
gallbladder
.
Diseases
Validation
Diseases presenting
"small cell carcinoma of the gallbladder"
symptom
carcinoma of the gallbladder
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