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Curative resection of combined neuroendocrine carcinoma and adenocarcinoma of the gallbladder.
[carcinoma of the gallbladder]
Neuroendocrine
carcinoma
of
the
gallbladder
has
very
rarely
been
reported
as
it
accounts
for
only
0
.
5
%
of
all
neuroendocrine
tumors
.
It
has
a
very
aggressive
biological
behavior
.
These
tumors
are
usually
diagnosed
at
an
advanced
stage
and
surgical
management
is
therefore
not
an
option
.
We
performed
a
hepatopancreaticoduodenectomy
along
with
adjuvant
chemotherapy
in
a
48
-
year
-old
patient
with
a
neuroendocrine
carcinoma
of
the
gallbladder
.
The
patient
has
been
followed
up
at
the
outpatient
clinic
for
18
months
without
there
having
been
any
recurrence
.
Patients
with
a
locally
invasive
neuroendocrine
carcinoma
in
the
gallbladder
may
benefit
from
aggressive
surgical
treatment
followed
by
adjuvant
chemotherapy
.
The
primary
management
in
high
-grade
metastatic
tumors
is
,
however
,
mainly
medical
.
Diseases
Validation
Diseases presenting
"locally invasive neuroendocrine carcinoma in the gallbladder"
symptom
carcinoma of the gallbladder
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