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Gallbladder carcinoma with skeletal metastasis in a Nigerian woman: a case report and review of literature.
[carcinoma of the gallbladder]
To
present
a
case
of
skeletal
metastasis
from
a
gallbladder
malignancy
,
a
rare
occurrence
.
A
75
year
old
Nigerian
woman
presented
in
the
surgical
outpatient
clinic
of
the
University
of
Port
Harcourt
Teaching
Hospital
with
a
two
month
history
of
right
hypochondrial
pain
and
three
weeks
swelling
on
the
forehead
.
Physical
examination
revealed
an
ill
looking
,
emaciated
elderly
woman
in
mild
painful
distress
.
She
was
pale
,
afebrile
and
anicteric
.
Skull
x-
ray
revealed
a
well
circumscribed
soft
tissue
mass
over
a
lytic
bone
defect
in
the
frontal
region
.
Abdominal
ultrasound
scan
showed
an
enlarged
gallbladder
with
a
thickened
wall
and
intraluminal
echogenic
mass
,
surrounding
lymphadenopathy
and
intrahepatic
metastasis
.
Radiological
diagnosis
of
advanced
gallbladder
carcinoma
with
both
local
and
distant
metastases
was
made
.
Carcinoma
of
the
gallbladder
with
skeletal
metastasis
is
a
rare
finding
.
However
,
in
any
patient
with
gallbladder
malignancy
distant
metastasis
with
skeletal
involvement
should
be
sought
.
Diseases
Validation
Diseases presenting
"lytic bone defect in the frontal region"
symptom
carcinoma of the gallbladder
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