Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
[Association of cytochrome P4502D6 gene polymorphism with the susceptibility of heroin spongiform leucoencephalopathy].
[canavan disease]
To
elucidate
the
relation
between
cytochrome
P
4502
D
6
(
CYP
2
D
6
)
gene
polymorphism
and
the
susceptibility
of
heroin
spongiform
leucoencephalopathy
(
HSLE
)
.
With
polymerase
chain
reaction-restriction
fragment
length
polymorphism
technique
,
the
cytochrome
P
4502
D
6
gene
polymorphisms
were
analyzed
in
HSLE
cases
and
control
subjects
.
The
frequencies
of
CYP
2
D
6
(
CYP
2
D
6
/
C
188
,
CYP
2
D
6
/
L
2938
,
CYP
2
D
6
/
G
4268
)
gene
mutations
were
higher
in
HSLE
patients
than
in
the
controls
.
The
CYP
2
D
6
gene
mutation
is
associated
with
a
high
risk
of
HSLE
.
