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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy without anterior temporal pole involvement: a case report.
[cadasil]
The
location
of
white
matter
lesions
,
especially
in
the
anterior
temporal
poles
(
ATP
)
,
is
helpful
in
the
diagnosis
of
cerebral
autosomal
dominant
arteriopathy
with
subcortical
infarcts
and
leukoencephalopathy
(
CADASIL
)
.
We
report
a
49
-
year
-old
man
with
CADASIL
who
developed
migraine
with
atypical
aura
,
silent
lacunar
infarcts
,
and
leukoencephalopathy
without
involvement
of
the
ATP
.
The
prevalence
of
migraine
with
aura
in
subjects
with
CADASIL
is
several
times
greater
than
that
in
the
general
population
.
Particularly
in
patients
with
CADASIL
,
the
aura
is
often
atypical
(
hemiplegic
,
basilar
,
or
prolonged
)
.
A
diagnosis
of
CADASIL
should
be
considered
in
patients
with
lacunar
infarcts
,
leukoencephalopathy
,
and
migraine
with
atypical
aura
,
even
in
the
absence
of
white
matter
lesion
in
the
ATPs
.
Diseases
Validation
Diseases presenting
"silent lacunar infarcts"
symptom
cadasil
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