Early dietary treatments with Lorenzo's oil and docosahexaenoic acid for neurological development in a case with Zellweger syndrome.

[zellweger syndrome]

We treated a girl with Zellweger syndrome using a special infant formula supplemented with middle chain triglyceride (MCT ) milk , docosahexaenoic acid (DHA ), Lorenzo 's oil , and Lunaria oil , which is rich in nervonic acid (C 2 4 :1 ). We examined the fatty acid contents of the plasma and red blood cell (RBC ) membrane . Neurological development was evaluated using Denver developmental screening test and auditory brainstem response (ABR ). Her delayed neurological development , liver dysfunction , and cholestasis were all improved 2 weeks after starting the dietary treatment . DHA level in RBC membranes was increased and very long chain fatty acid (VLCFA ,C 2 6 :0 ) levels were decreased . Our findings suggest that the dietary treatment with combination of MCT milk , DHA , Lorenzo 's oil , and Lunaria oil in the patients with Zellweger syndrome bring some benefits for neurological development .

Diseases
Validation

Diseases presenting "auditory brainstem response" symptom

zellweger syndrome

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