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Fuzzy scaling analysis of a mouse mutant with brain morphological changes.
[zellweger syndrome]
Scaling
behavior
inherently
exists
in
fundamental
biological
structures
,
and
the
measure
of
such
an
attribute
can
only
be
known
at
a
given
scale
of
observation
.
Thus
,
the
properties
of
fractals
and
power-law
scaling
have
become
attractive
for
research
in
biology
and
medicine
because
of
their
potential
for
discovering
patterns
and
characteristics
of
complex
biological
morphologies
.
Despite
the
successful
applications
of
fractals
for
the
life
sciences
,
the
quantitative
measure
of
the
scale
invariance
expressed
by
fractal
dimensions
is
limited
in
more
complex
situations
,
such
as
for
histopathological
analysis
of
tissue
changes
in
disease
.
In
this
paper
,
we
introduce
the
concept
of
fuzzy
scaling
and
its
analysis
of
a
mouse
mutant
with
postnatal
brain
morphological
changes
.