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Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men.
[aromatase deficiency]
The
report
focuses
on
the
role
of
estrogens
in
human
male
,
dealing
with
two
human
models
of
congenital
estrogen
deficiency
:
estrogen
resistance
and
aromatase
deficiency
.
Similarities
and
differences
of
clinical
phenotypes
of
these
models
are
described
and
progresses
of
estrogen
treatment
of
aromatase-
deficient
men
are
reported
.
Finally
,
the
putative
use
of
estrogen
in
men
and
the
use
of
aromatase
inhibitors
and
antiestrogen
for
male
disorders
are
discussed
.