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Sex steroids and sexual desire in a man with a novel mutation of aromatase gene and hypogonadism.
[aromatase deficiency]
Sexual
behavior
was
investigated
by
a
sexological
interview
in
a
man
with
aromatase
deficiency
and
hypogonadism
.
The
study
was
performed
at
the
end
of
a
long
testosterone
treatment
,
during
transdermal
estradiol
treatment
and
during
estradiol
and
testosterone
associated
treatment
.
Sexual
behavior
did
not
show
abnormalities
.
As
assessed
by
a
sexological
interview
and
by
a
sexological
questionnaire
gender-identity
was
male
,
sexual
orientation
was
heterosexual
and
libido
was
normal
.
Sexual
function
was
limited
to
masturbation
and
was
seemingly
unaffected
by
testosterone
or
estradiol
alone
;
only
the
associated
treatment
induced
a
great
increase
in
libido
and
in
frequency
of
masturbation
and
sexual
fantasies
when
both
testosterone
and
estradiol
reached
the
range
of
normality
.
Sexual
behavior
is
mainly
under
the
control
of
cognitive
functions
in
men
,
but
sex
steroids
may
modulate
some
aspects
of
male
sexuality
.
Our
findings
suggest
that
in
men
estrogens
could
play
a
role
in
sexual
activity
.
