Affinity for music in Wolf-Hirschhorn syndrome: two case reports.

[wolf-hirschhorn syndrome]

Wolf-Hirschhorn syndrome is a congenital malformation syndrome resulting from deletion of the short arm of chromosome 4 . Individuals with Wolf-Hirschhorn syndrome may have a "Greek warrior helmet " appearance , growth retardation , developmental delay , muscular hypotonia , epilepsy , and difficulty with language including verbal communication . An affinity for music has not previously been reported in these patients .We describe two patients with Wolf-Hirschhorn syndrome who both have a strong affinity for music . One patient is a 20 -year -old woman who likes to listen to music all day and can hum many tunes . The other patient is a 9 -year -old girl who is calmed by music and received music therapy , with subsequent improvement in her communication skills (eye contact , joint attention , and vocalizations to request music ).Individuals with Wolf-Hirschhorn syndrome may have a strong affinity for music and may benefit from music therapy . Additional studies are needed to investigate the interest in music in individuals with Wolf-Hirschhorn syndrome .