Rare Diseases Symptoms Automatic Extraction
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A random Abstract
Our Project
Our Team
Primary immunodeficiency investigation in patients during and after hospitalization in a pediatric intensive care unit.
[wiskott-aldrich syndrome]
To
analyze
whether
the
patients
with
severe
infections
,
admitted
in
the
Pediatric
Intensive
Care
Unit
of
the
Hospital
de
ClÃnicas
of
the
Universidade
Federal
de
Uberlândia
,
underwent
the
active
screening
for
primary
immunodeficiencies
(
PID
)
.
Retrospective
study
that
assessed
the
data
records
of
patients
with
any
severe
infections
admitted
in
the
Pediatric
Intensive
Care
Unit
,
covering
a
period
from
January
2011
to
January
2012
,
in
order
to
confirm
if
they
performed
an
initial
investigation
for
PID
with
blood
count
and
immunoglobulin
dosage
.
In
the
studied
period
,
53
children
were
hospitalized
with
severe
infections
in
the
Pediatric
Intensive
Care
Unit
,
and
only
in
seven
(
13
.
2
%
)
the
initial
investigation
of
PID
was
performed
.
Among
these
patients
,
3
/
7
(
42
.
8
%
)
showed
quantitative
alterations
in
immunoglobulin
G
(
IgG
)
levels
,
1
/
7
(
14
.
3
%
)
had
the
diagnosis
of
cyclic
neutropenia
,
and
1
/
7
(
14
.
3
%
)
presented
thrombocytopenia
and
a
final
diagnosis
of
Wiskott-
Aldrich
syndrome
.
Therefore
,
the
PID
diagnosis
was
confirmed
in
5
/
7
(
71
.
4
%
)
of
the
patients
.
The
investigation
of
PID
in
patients
with
severe
infections
has
not
been
routinely
performed
in
the
Pediatric
Intensive
Care
Unit
.
Our
findings
suggest
the
necessity
of
performing
PID
investigation
in
this
group
of
patients
.
Diseases
Validation
Diseases presenting
"thrombocytopenia"
symptom
22q11.2 deletion syndrome
adrenomyeloneuropathy
dedifferentiated liposarcoma
erythropoietic protoporphyria
esophageal adenocarcinoma
heparin-induced thrombocytopenia
hodgkin lymphoma, classical
holt-oram syndrome
homocystinuria without methylmalonic aciduria
liposarcoma
malignant atrophic papulosis
monosomy 21
oculocutaneous albinism
scrub typhus
sneddon syndrome
typhoid
waldenström macroglobulinemia
wiskott-aldrich syndrome
This symptom has already been validated
