Diabetes mellitus and cancer in Werner syndrome.

[werner syndrome]

Onishi et al . recently reported here an association of diabetes mellitus (DM ) with neoplasm type in newly identified patients with Werner syndrome (WS ), an autosomal recessive cancer predisposition syndrome with features of premature aging that include a high risk of DM (Onishi et al . in Acta Diabetol 49 (Suppl 1 ):259 -260 , 2012 ; Epstein et al . in Medicine 45 :177 -121 , 1966 ). In contrast , we did not detect an association between DM and neoplasm type in an independent WS cohort we assembled to determine the histopathologic spectrum and type -specific risk of neoplasia in WS .