Atypical lipomatous tumor/well-differentiated liposarcoma: what is it?

[well-differentiated liposarcoma]

Liposarcoma (LPS ) is the most common soft tissue sarcoma , frequently found in the thigh and retroperitoneum . LPS is commonly classified into well-differentiated LPS and dedifferentiated LPS . Histologic subtype , tumor location , and completeness of surgical resection are important prognostic indicators for LPS . Magnetic resonance imaging best characterizes extremity lesions , whereas computed tomography is most often used for intra-abdominal and retroperitoneal tumors . Surgical resection is the mainstay of treatment . Adjuvant radiation is considered for close margins . Survival for extremity tumors is favorable . However , difficulty in obtaining wide margins in the retroperitoneum predisposes to local recurrence and , ultimately , death from unresectable disease .