Massive localized lymphedema: A case series and literature review.

[well-differentiated liposarcoma]

A large , deep , soft tissue mass is often malignant in nature ; however , a recent study described a large soft tissue mass present in morbidly obese patients that was found to be benign . Massive localized lymphedema (MLL ) is a large pedunculated lymphadematous mass found in the lower extremity of morbidly obese patients . MLL often enlarges over many years and may interfere with mobility . Although histologically similar to well-differentiated liposarcoma , MLL has recently emerged as a separate , benign clinical entity . The pathophysiology of MLL is yet to be understood . A literature review , and the authors ' experiences are discussed to assist in clinical decision making .