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[Dedifferentiated Liposarcoma with Peculiar Meningothelial-Like Whorling and Metaplastic Bone Formation, Case Report.]
[well-differentiated liposarcoma]
Dedifferentiated
liposarcoma
represents
a
both
morphologically
and
biologically
fascinating
lesion
in
which
transition
from
low
-grade
to
high
-grade
nonlipogenic
morphology
within
a
well-differentiated
liposarcoma
is
observed
.
A
peculiar
form
of
dedifferentiated
liposarcoma
characterized
by
a
nonlipogenic
component
with
a
meningothelial-
like
whorling
pattern
of
growth
and
metaplastic
bone
formation
has
been
described
.
A
59
-
year
-old
man
presented
with
a
pelvic
retroperitoneal
mass
measuring
13
x
10
x
8
cm
.
Histopathologically
the
mass
consisted
almost
entirely
of
a
dedifferentiated
nonlipogenic
component
with
meningothelial-like
whorling
pattern
,
metaplastic
cartilage
and
bone
.
Dedifferentiated
liposarcoma
with
meningothelial-
like
whorling
pattern
has
rarely
been
encountered
.
Here
,
we
report
this
case
because
of
the
problems
in
differential
diagnosis
especially
for
cases
that
have
an
extensive
dedifferentiated
component
and
the
uncertainty
of
the
biological
behavior
of
these
tumors
.
Diseases
Validation
Diseases presenting
"the uncertainty of the biological behavior of these tumors"
symptom
dedifferentiated liposarcoma
well-differentiated liposarcoma
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