Neurologic complications of disorders of the adrenal glands.

[von hippel-lindau disease]

Disorders of the adrenal glands frequently have secondary neurological manifestations , while some diseases that involve the central nervous system are accompanied by adrenal gland dysfunction . Excessive corticosteroid secretions in primary or secondary Cushing 's syndrome causes muscle weakness and behavioral disturbances , such as emotional lability and sometimes depression , while adrenal insufficiency may cause fatigue , weakness , and depression . Adrenoleukodystrophy and adrenoneuromyelopathy are X-linked recessive disorders of the metabolism of very long chain fatty acids that manifest with white matter abnormalities of the brain , myelopathy and /or neuropathy , as well as adrenal insufficiency . Other disorders of the adrenal glands include hyperaldosteroidism , which may cause weakness from hypokalemia . Dysfunction of the adrenal medulla causes excessive or deficient secretion of catecholamines , primarily causing cardiovascular symptoms . This chapter reviews the clinical manifestations and diagnostic aspects and treatment of the various disorders of the adrenal glands . Some of the congenital adrenal diseases are also discussed .

Diseases
Validation

Diseases presenting "fatigue" symptom

benign recurrent intrahepatic cholestasis

cholangiocarcinoma

congenital adrenal hyperplasia

cowden syndrome

cutaneous mastocytosis

dedifferentiated liposarcoma

dracunculiasis

erdheim-chester disease

esophageal carcinoma

fabry disease

familial hypocalciuric hypercalcemia

familial mediterranean fever

hydrocephalus with stenosis of the aqueduct of sylvius

inclusion body myositis

kabuki syndrome

lymphangioleiomyomatosis

neuralgic amyotrophy

pleomorphic liposarcoma

systemic capillary leak syndrome

triple a syndrome

typhoid

von hippel-lindau disease

waldenstrÃ¶m macroglobulinemia

x-linked adrenoleukodystrophy

This symptom has already been validated