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[Clinical study on patients with renal-cell carcinoma accompanied with von hippel lindau disease treated with radiofrequency ablation].
[von hippel-lindau disease]
We
report
12
renal
cell
carcinomas
in
6
patients
with
Von
Hippel-
Lindau
(
VHL
)
disease
treated
with
radiofrequency
ablation
(
RFA
)
.
The
mean
age
of
the
patients
was
46
(
range
38
-
53
)
years
(
male
:
4
,
female
:
2
)
.
Computed
tomography
(
CT
)
-
guided
transcutaneous
RFA
was
performed
under
conscious
sedation
with
local
anesthetics
.
The
mean
size
of
the
tumors
was
2
.
4
(
range
0
.
7
-
8
.
1
)
cm
.
Nine
of
the
12
tumors
(
75
%
)
were
locally
well
controlled
.
However
,
3
tumors
in
2
patients
developed
visceral
metastases
after
RFA
.
While
minimal
flank
pain
,
nausea
,
perinephritic
hematoma
and
lumbago
were
observed
,
there
was
no
major
complication
during
or
after
the
procedure
.
The
therapy
with
CT
-guided
transcutaneous
RFA
is
efficient
and
minimal
invasive
for
renal
cell
carcinoma
in
patients
with
VHL
,
leading
to
preservation
of
renal
function
.
