Vaccine-induced inflammation attenuates the vascular responses to mental stress.

[typhoid]

Inflammation is associated with poorer vascular function , with evidence to suggest that inflammation can also impair the vascular responses to mental stress . This study examined the effects of vaccine-induced inflammation on vascular responses to mental stress in healthy participants . Eighteen male participants completed two stress sessions : an inflammation condition having received a typhoid vaccination and a control (non-inflamed ) condition . Tumor necrosis factor -alpha and interleukin-6 (p 's <.001 ) increased following vaccination , confirming modest increases in inflammation . Mental stress increased blood flow , blood pressure , heart rate , and cardiac output in both conditions (all p 's <.001 ), but the blood flow response to stress was attenuated having received the vaccination compared to the control condition (p 's <.05 ). These results further implicate the interaction between inflammation and the vasculature as a mechanism through which stress may trigger myocardial infarction .

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Diseases presenting "blood pressure" symptom

acute rheumatic fever

adrenal incidentaloma

alpha-thalassemia

cadasil

congenital adrenal hyperplasia

congenital diaphragmatic hernia

cushing syndrome

fabry disease

familial mediterranean fever

lymphangioleiomyomatosis

pendred syndrome

proteus syndrome

scrub typhus

systemic capillary leak syndrome

thoracic outlet syndrome

typhoid

von hippel-lindau disease

werner syndrome

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