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Predictors of mortality in children with typhoid ileal perforation in a Nigerian tertiary hospital.
[typhoid]
Childhood
typhoid
ileal
perforation
is
associated
with
high
morbidity
and
mortality
.
Our
aim
was
to
ascertain
the
predictors
of
survival
in
children
.
This
is
a
tertiary
hospital-based
retrospective
review
of
patients
aged
≤
15
Â
years
managed
for
typhoid
ileal
perforations
between
January
2005
and
December
2013
.
The
details
of
their
biodata
,
potential
risk
factors
and
outcome
were
evaluated
.
Forty
-
five
children
out
of
a
total
of
97
with
typhoid
fever
had
typhoid
ileal
perforation
.
The
age
range
was
2
-
15
Â
years
,
mean
(
±
SD
)
Â
=
Â
9
.
3
(
±
3
.
31
)
years
,
median
Â
=
Â
10
Â
years
.
There
were
more
males
than
females
(
26
:
19
)
.
Thirty
-
nine
(
86
.
7
Â
%
)
patients
were
>
5
Â
years
old
.
There
were
nine
deaths
(
20
Â
%
mortality
)
.
The
mean
(
±
SD
)
age
of
survivors
was
9
.
8
(
±
2
.
9
)
years
and
7
.
1
(
±
4
.
2
)
for
non-survivors
(
p
Â
=
Â
0
.
026
)
.
The
duration
of
illness
at
presentation
,
gender
,
admission
temperature
,
nutritional
status
and
packed
cell
volume
,
perforation-operation
interval
,
number
of
perforations
,
surgical
procedure
,
and
the
duration
of
surgery
did
not
statistically
influence
survival
(
p
Â
>
Â
0
.
05
)
.
The
age
of
the
patients
and
burst
abdomen
attained
statistical
significance
(
p
Â
<
Â
0
.
05
)
.
The
patients
'
age
and
postoperative
burst
abdomen
were
significant
determinants
of
survival
in
children
with
typhoid
ileal
perforation
.
Diseases
Validation
Diseases presenting
"fever"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
alexander disease
allergic bronchopulmonary aspergillosis
canavan disease
carcinoma of the gallbladder
child syndrome
congenital toxoplasmosis
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
esophageal adenocarcinoma
esophageal carcinoma
familial mediterranean fever
focal myositis
hodgkin lymphoma, classical
lamellar ichthyosis
legionellosis
locked-in syndrome
malignant atrophic papulosis
neonatal adrenoleukodystrophy
neuralgic amyotrophy
oculocutaneous albinism
papillon-lefèvre syndrome
pyomyositis
pyruvate dehydrogenase deficiency
scrub typhus
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
typhoid
waldenström macroglobulinemia
wolf-hirschhorn syndrome
This symptom has already been validated