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Allgrove'S syndrome: case report and literature review.
[triple a syndrome]
This
report
concerns
two
brothers
aged
10
and
18
years
with
long
-standing
dysphagia
that
started
at
age
three
and
six
years
respectively
.
They
had
been
diagnosed
as
achalasia
and
treated
accordingly
.
The
appearance
of
additional
symptoms
and
clinical
signs
required
further
investigations
including
abdominal
sonography
,
esophago-gastroduodenoscopy
,
barium
swallow
,
esophageal
manometry
,
computerized
tomography
(
CT
)
of
abdomen
and
brain
,
biochemical
profiles
,
and
neurologic
and
ophthalmic
evaluations
.
The
results
of
these
extensive
investigations
along
with
the
clinical
evaluations
were
consistent
with
Allgrove
's
syndrome
.
Glucocorticoid
therapy
was
initiated
.
The
management
consisted
of
pneumatic
cardiac
dilatation
and
initiation
of
cortisone
treatment
.
The
patients
'
response
was
impressive
and
they
resumed
most
of
their
usual
activities
.
Diseases
Validation
Diseases presenting
"dysphagia"
symptom
alexander disease
cadasil
cushing syndrome
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
inclusion body myositis
kindler syndrome
liposarcoma
locked-in syndrome
neuralgic amyotrophy
oligodontia
triple a syndrome
well-differentiated liposarcoma
This symptom has already been validated