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Pharmacomechanical thrombolysis in the management of paget-schroetter syndrome.
[thoracic outlet syndrome]
Paget
-
Schroetter
syndrome
(
PSS
)
is
a
rare
form
of
thoracic
outlet
syndrome
caused
by
axillosubclavian
vein
thrombosis
which
typically
presents
in
healthy
young
adults
.
Prompt
therapy
,
traditionally
by
means
of
catheter-directed
thrombolysis
(
CDT
)
prior
to
definitive
surgery
,
can
prevent
the
subsequent
onset
of
postthrombotic
syndrome
(
PTS
)
and
considerable
disability
.
As
CDT
is
associated
with
major
haemorrhage
and
high
overall
treatment
cost
,
pharmacomechanical
thrombectomy
(
PMT
)
seems
to
be
an
attractive
alternative
which
combines
pharmacological
thrombolysis
with
mechanical
clot
disruption
.
The
Trellis-
8
peripheral
infusion
catheter
is
an
example
of
such
a
treatment
which
provides
topical
thrombolysis
in
an
isolated
zone
.
We
describe
the
use
of
the
Trellis-
8
PMT
system
in
the
successful
management
of
three
patients
with
PSS
.
