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Comparison of blood pool and extracellular gadolinium chelate for functional MR evaluation of vascular thoracic outlet syndrome.
[thoracic outlet syndrome]
To
compare
performance
of
single
-injection
blood
pool
agent
(
gadofosveset
trisodium
,
BPA
)
against
dual-injection
extracellular
contrast
(
gadopentetate
dimeglumine
,
ECA
)
for
MRA
/
MRV
in
assessment
of
suspected
vascular
TOS
.
Thirty
-
one
patients
referred
for
vascular
TOS
evaluation
were
assessed
with
BPA
(
n
=
18
)
or
ECA
(
n
=
13
)
MRA
/
MRV
in
arm
abduction
and
adduction
.
Images
were
retrospectively
assessed
for
:
image
quality
(
1
=
non-diagnostic
,
5
=
excellent
)
,
vessel
contrast
(
1
=
same
signal
as
muscle
,
4
=
much
brighter
than
muscle
)
and
vascular
pathology
by
two
independent
readers
,
with
a
separate
experienced
reader
providing
reference
assessment
of
vascular
pathology
.
Median
image
quality
was
diagnostic
or
better
(
score
≥
3
)
for
ECA
and
BPA
at
all
time
points
,
with
BPA
image
quality
superior
at
abduction
late
(
BPA
4
.
5
,
ECA
4
,
p
=
0
.
042
)
and
ECA
image
quality
superior
at
adduction-
early
(
BPA
4
.
5
;
ECA
4
.
0
,
p
=
0
.
018
)
.
High
qualitative
vessel
contrast
(
mean
score
≥
3
)
was
observed
at
all
time
points
with
both
BPA
and
ECA
,
with
superior
BPA
vessel
contrast
at
abduction-
late
(
BPA
3
.
97
±
0
.
12
;
ECA
3
.
73
±
0
.
26
,
p
=
0
.
007
)
and
ECA
at
adduction-
early
(
BPA
3
.
42
±
0
.
52
;
ECA
3
.
96
±
0
.
14
,
p
<
0
.
001
)
.
Readers
readily
identified
arterial
and
venous
pathology
with
BPA
,
similar
to
ECA
examinations
.
Single
-injection
BPA
MRA
/
MRV
for
TOS
evaluation
demonstrated
diagnostic
image
quality
and
high
vessel
contrast
,
similar
to
dual-injection
ECA
imaging
,
enabling
identification
of
fixed
and
functional
arterial
and
venous
pathology
.
Diseases
Validation
Diseases presenting
"venous pathology"
symptom
thoracic outlet syndrome
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