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A random Abstract
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In vivo confocal microscopy of congenital aniridia-associated keratopathy.
[aniridia]
To
explore
the
in
vivo
morphological
changes
of
cornea
and
limbus
in
aniridia
-associated
keratopathy
(
AAK
)
.
Three
cases
of
AAK
were
examined
with
the
application
of
in
vivo
confocal
microscopy
(
IVCM
)
.
Abnormal
structure
of
wing
and
basal
layer
of
epithelium
,
the
loss
of
subbasal
nerves
,
and
the
presence
of
goblet
cells
at
central
cornea
could
be
identified
in
the
most
severe
case
,
along
with
the
absence
of
Vogt
palisades
.
The
less
extent
of
abnormalities
in
corneal
epithelial
cells
,
subbasal
nerve
,
and
Vogt
palisades
were
visible
in
the
moderate
or
mild
cases
.
The
morphological
changes
of
cornea
and
limbus
vary
in
AAK
,
and
IVCM
is
a
promising
tool
to
determine
the
degree
of
limbal
stem
cell
deficiency
in
patients
with
AAK
.
Diseases
Validation
Diseases presenting
"basal layer"
symptom
aniridia
epidermolysis bullosa simplex
esophageal adenocarcinoma
harlequin ichthyosis
junctional epidermolysis bullosa
kindler syndrome
oral submucous fibrosis
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