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[Chronic edema, monoclonal dysglobulinemia and profuse telangiectasia: a distinct entity?].
[systemic capillary leak syndrome]
Monoclonal
gammopathy
and
edema
are
features
encountered
during
several
diseases
,
especially
systemic
capillary
leak
syndrome
.
The
diagnoses
of
POEMS
syndrome
,
edematous
systemic
scleroderma
and
a
fortuitous
association
may
be
also
discussed
.
We
report
the
cases
of
two
patients
which
did
not
fulfill
the
criteria
for
such
diagnoses
.
Although
the
2
cases
share
some
discrepancies
,
they
have
also
similar
and
particular
features
:
association
of
chronic
edema
,
monoclonal
gammopathy
and
profuse
and
acquired
telangiectasias
.
The
meaning
of
these
cases
remains
to
be
clarified
.
It
might
be
an
entity
close
to
the
systemic
capillary
leak
syndrome
but
characterized
by
the
chronicity
of
edema
and
by
a
distinct
cutaneous
sign
,
the
occurrence
of
numerous
telangiectasias
.
These
cases
emphasize
that
the
acquired
and
profuse
telangiectasias
belong
to
the
wide
range
of
cutaneous
abnormalities
which
may
be
associated
with
monoclonal
paraproteinemia
.
Diseases
Validation
Diseases presenting
"a fortuitous association may be also discussed"
symptom
systemic capillary leak syndrome
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