[Chronic edema, monoclonal dysglobulinemia and profuse telangiectasia: a distinct entity?].

[systemic capillary leak syndrome]

Monoclonal gammopathy and edema are features encountered during several diseases , especially systemic capillary leak syndrome . The diagnoses of POEMS syndrome , edematous systemic scleroderma and a fortuitous association may be also discussed . We report the cases of two patients which did not fulfill the criteria for such diagnoses .Although the 2 cases share some discrepancies , they have also similar and particular features : association of chronic edema , monoclonal gammopathy and profuse and acquired telangiectasias .The meaning of these cases remains to be clarified . It might be an entity close to the systemic capillary leak syndrome but characterized by the chronicity of edema and by a distinct cutaneous sign , the occurrence of numerous telangiectasias . These cases emphasize that the acquired and profuse telangiectasias belong to the wide range of cutaneous abnormalities which may be associated with monoclonal paraproteinemia .